Investigation of the Antioxidant and Antitumour Properties of Some Cyclobutane Ring Containing 2,5-Thiophene Diacyl Compounds

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dc.contributor.authorGuler, Alpay
dc.contributor.authorKaratepe, Arzu
dc.contributor.authorKoparir, Pelin
dc.contributor.authorPekdemir, Sibel
dc.contributor.authorKaratepe, Mustafa
dc.date.accessioned2026-08-12T16:57:09Z
dc.date.issued2022
dc.departmentFırat Üniversitesi
dc.description.abstractIn this research. the effect of thiophene derivatives on the (MDA) concentration which is an indicator of lipid peroxidation. antioxidant vitamins A E and in itro antioxidant activity and antitumor activity, were investigated in cell culture media. In the comparison done among groups. it was observed that MDA and vitamin A concentrations were statistically (P<0,05) changed, Looking at the measured parameters during the experiment. the number of live cells. the compounds is an effective antitumor activity in the L 1210 cell types. The oxidative stress parameters are used for all compounds.
dc.description.sponsorshipManagement Unit of Scientific Research Projects of Firat University (FUBAP) [FUBAP 2120]
dc.description.sponsorshipThe financial support of The Management Unit of Scientific Research Projects of Firat University (FUBAP), (Project Number FUBAP 2120).
dc.identifier.doi10.33263/BRIAC122.24502461
dc.identifier.endpage2461
dc.identifier.issn2069-5837
dc.identifier.issue2
dc.identifier.orcid0000-0002-3981-9748
dc.identifier.orcid0000-0001-6358-5913
dc.identifier.scopus2-s2.0-85110076280
dc.identifier.scopusqualityQ2
dc.identifier.startpage2450
dc.identifier.urihttps://doi.org/10.33263/BRIAC122.24502461
dc.identifier.urihttps://hdl.handle.net/11508/46336
dc.identifier.volume12
dc.identifier.wosWOS:000665770100081
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBiointerface Research Applied Chemistry
dc.relation.ispartofBiointerface Research in Applied Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260511
dc.subjectHPLC
dc.subjectthiophene
dc.subjectcyclobutane
dc.subjectMDA
dc.subjectantioxidant activity
dc.subjectantitumour activity
dc.titleInvestigation of the Antioxidant and Antitumour Properties of Some Cyclobutane Ring Containing 2,5-Thiophene Diacyl Compounds
dc.typeArticle

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