In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4-Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole

Abstract

1,3,4-Thiadiazoles have a variety of biological activities depending on their substituents. This study aims to investigate the in vitro antioxidant properties of 1R,2R -1,2-bis- (5- (4-hydroxynaphthalen-1-ylazo) - [1,3,4] thiadiazol-2-yl) -ethane- 1,2-diole novel compound. In this study, antioxidant activities were measured by different methods such as, DPPH. radical scavenging activity, iron reducing power capacity, metal chelating activity and hydroxyl radical scavenging activity. As a result, it was determined that this new compound has effective antioxidant and free radical scavenging activity when compared to reference antioxidants such as BHT and ?-tocopherol.