Synthesis, antibacterial and antifungal activity of some new thiazolylhydrazone derivatives containing 3-substituted cyclobutane ring

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dc.contributor.authorCukurovali, A
dc.contributor.authorYilmaz, I
dc.contributor.authorGur, S
dc.contributor.authorKazaz, C
dc.date.accessioned2026-08-12T17:44:32Z
dc.date.issued2006
dc.departmentFırat Üniversitesi
dc.description.abstractA series of Schiff bases, combining 2,4-disubstituted thiazole and cyclobutane rings, and hydrazone moieties in the same molecule, was synthesized, characterized and evaluated for screening antibacterial and antifungal activities on microorganisms, respectively, on four bacteria and Candida tropicalis. The structures of original compounds were confirmed by analytical and spectroscopic (FT-IR, H-1 NMR and C-13 NMR) methods and elemental analysis. Both the antibacterial and antifungal activities and MIC values of compounds were reported. Among the tested compounds, the most effective compound providing a MIC value of 16 mu g ml(-1) are 2 against C. tropicalis and Bacillus subtilis and 3 against B. subtilis only. (c) 2005 Elsevier SAS. All rights reserved.
dc.identifier.doi10.1016/j.ejmech.2005.01.013
dc.identifier.endpage207
dc.identifier.issn0223-5234
dc.identifier.issue2
dc.identifier.orcid0000-0002-5249-0895
dc.identifier.pmid16378662
dc.identifier.scopus2-s2.0-33644950839
dc.identifier.scopusqualityQ1
dc.identifier.startpage201
dc.identifier.urihttps://doi.org/10.1016/j.ejmech.2005.01.013
dc.identifier.urihttps://hdl.handle.net/11508/60311
dc.identifier.volume41
dc.identifier.wosWOS:000236643200005
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier France-Editions Scientifiques Medicales Elsevier
dc.relation.ispartofEuropean Journal of Medicinal Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260511
dc.subjectcyclobutane
dc.subjectthiosemicarbazone
dc.subjectantibacterial activity
dc.subjectantifungal activity
dc.subjectMIC
dc.titleSynthesis, antibacterial and antifungal activity of some new thiazolylhydrazone derivatives containing 3-substituted cyclobutane ring
dc.typeArticle

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