Modeling dysentery spread and the impact of public awareness on control dynamics

dc.contributor.authorAhmed, Karim K.
dc.contributor.authorYusuf, Jibrin Sale
dc.contributor.authorAliyu, Aliyu Isa
dc.contributor.authorAgaie, Baba Galadima
dc.contributor.authorYusuf, Abdulrazak Sale
dc.contributor.authorOzsahin, Ilker
dc.contributor.authorKhalifa, Abeer S.
dc.date.accessioned2026-08-12T17:42:42Z
dc.date.issued2025
dc.departmentFırat Üniversitesi
dc.description.abstractDysentery remains a leading cause of morbidity and mortality in developing regions, exacerbated by poor sanitation and limited access to healthcare. This study develops a novel mathematical model to analyze the transmission dynamics of dysentery and evaluate the effectiveness of control strategies, with a specific focus on the impact of public awareness. The model uniquely stratifies the population into compartments based on health education status and disease severity, allowing for a nuanced analysis of intervention impacts. We derived a key epidemiological threshold, the basic reproduction number, to determine the conditions for disease elimination or persistence. Our analysis demonstrates that a disease-free equilibrium is locally and globally stable when this threshold is below one. Furthermore, we employed optimal control theory to simulate and compare three intervention strategies: public awareness campaigns, hygiene and sanitation improvements, and treatment of infected individuals. Numerical simulations reveal that while each intervention alone reduces disease burden, a combined strategy is the most effective and cost-efficient approach to curtailing outbreaks. These findings underscore the critical importance of integrated public health policies that synergize education, prevention, and treatment for effective and sustainable dysentery control.
dc.identifier.doi10.1038/s41598-025-24286-z
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.orcid0000-0002-9845-681X
dc.identifier.pmid41254016
dc.identifier.scopus2-s2.0-105022222347
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1038/s41598-025-24286-z
dc.identifier.urihttps://hdl.handle.net/11508/59842
dc.identifier.volume15
dc.identifier.wosWOS:001618727000010
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNature Portfolio
dc.relation.ispartofScientific Reports
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260511
dc.subjectDysentery disease
dc.subjectEpidemiology
dc.subjectAwareness control
dc.titleModeling dysentery spread and the impact of public awareness on control dynamics
dc.typeArticle

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