QT interval dispersion in the patients with central serous chorioretinopathy

Abstract

AIM: To evaluate QT dispersion (QTD) in patients with central serous chorioretinopathy (CSC). METHODS: This clinical, comperative, case -control study included 30 patients with CSC at acute phase (Group 1) and 30 age- and sex-matched healthy subjects (Group 2, the control group). From all subjects, a 12-lead surface electrocardiography was obtained. The heart rate (HR), QT maximum (QT(max)), QT minimum (QT(min)), QT corrected (QT,), QTD and T-mean, were manually measured and analyzed. Student's t-test and Pearson's method of correlation were used for statistical analysis. RESULTS: The patient and control groups were matched for age, smoking status (rate and duration) and gender. There were no significant differences with regard to these among the groups (P>0.05). The participants included 19 men (63.3%) and 11 women (36.7%) in Group 1, 20 men (66.7%) and 10 women (33.3%) in Group 2. QTD and QT(c) were significantly higher than those of healthy controls (P<0.001 for QT(max), P=0.01 for QTD and P=0.001 for QT(c)). QT(min), T-mean and HR did not differ significantly between the study groups (P=0.28 for QT(min), P=0.56 for T-mean and P>0.05 for HR). No significant correlation was found between duration of the disorder and QTD values (r = 0.13, P > 0.05). CONCLUSION: These findings suggest that CSC may be associated with an increase in QTD and that the patients might be at risk for ventricular arrhythmia.