From Gut Dysbiosis to Skin Inflammation: Exploring the Hirschsprung's Disease-Psoriasis Link

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dc.contributor.authorYildirim, Harun
dc.contributor.authorDemir, Betul
dc.contributor.authorBakal, Unal
dc.contributor.authorUcer, Ozlem
dc.contributor.authorSevinc, Nur Sena
dc.contributor.authorYildirim, Ebru Aydin
dc.date.accessioned2026-08-12T17:11:11Z
dc.date.issued2026
dc.departmentFırat Üniversitesi
dc.description.abstractPsoriasis is a skin disease characterized by erythematous and scaly lesions, influenced by genetic and environmental factors. Hirschsprung disease (HD) is a congenital disorder associated with gut microbiome dysbiosis, which can trigger inflammatory skin conditions. We report a case of psoriasis vulgaris in a male infant with HD whose skin lesions completely resolved after HD treatment. This case highlights a potential link between HD-related gut dysbiosis and psoriasis.
dc.identifier.doi10.1111/pde.16036
dc.identifier.endpage144
dc.identifier.issn0736-8046
dc.identifier.issn1525-1470
dc.identifier.issue1
dc.identifier.orcid0000-0002-6190-5124
dc.identifier.orcid0009-0001-4064-4287
dc.identifier.orcid0000-0002-5140-8618
dc.identifier.orcid0009-0003-1233-0373
dc.identifier.orcid0009-0005-3672-630X
dc.identifier.pmid40801314
dc.identifier.scopus2-s2.0-105012972663
dc.identifier.scopusqualityQ2
dc.identifier.startpage141
dc.identifier.urihttps://doi.org/10.1111/pde.16036
dc.identifier.urihttps://hdl.handle.net/11508/51051
dc.identifier.volume43
dc.identifier.wosWOS:001548509400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPediatric Dermatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260511
dc.subjectdysbiosis
dc.subjectHirschsprung disease
dc.subjectpsoriasis
dc.titleFrom Gut Dysbiosis to Skin Inflammation: Exploring the Hirschsprung's Disease-Psoriasis Link
dc.typeArticle

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