Designing a novel radial basis neural structure for solving the dynamical hepatitis C virus model

dc.contributor.authorSabir, Zulqurnain
dc.contributor.authorYessengaliyev, Adilkazy
dc.contributor.authorTemirzhan, Abdikhalyk
dc.contributor.authorKoyunbakan, Hikmet
dc.contributor.authorBhatti, Saira
dc.contributor.authorNicolas, Rana
dc.date.accessioned2026-08-12T17:42:51Z
dc.date.issued2025
dc.departmentFırat Üniversitesi
dc.description.abstractThe purpose of the current investigation is to design a novel radial basis neural network for solving the dynamical hepatitis C virus model in patients with a high baseline viral load, which represents the nonlinear dynamical structure. The infection and treatment in the hepatitis C virus comprise uninfected hepatocytes, creatively infected hepatocytes, and viruses. The aim of this study is to solve the dynamical hepatitis C virus model in patients with a high baseline viral load with the optimization of the Bayesian regularization scheme. A database reference solution is achieved by the explicit Runge-Kutta in interval 0 and 1 with the step size of 0.01 by data division into training as 72%, while 14%, 14% for endorsement, and testing. Twenty numbers of neurons, a feed forward neural network, activation radial basis function, and the optimization Bayesian regularization approach have been used to solve the hepatitis C virus model. The precision of the scheme is perceived by the outcomes overlapping and the reducible absolute error values, which are found as 10-06 to 10-08. A statistical evaluation utilizing various operators and proportional approaches is carried out in order to assess the solver's efficiency.
dc.identifier.doi10.1038/s41598-025-29644-5
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.orcid0000-0002-7664-1467
dc.identifier.pmid41423703
dc.identifier.scopus2-s2.0-105026497743
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1038/s41598-025-29644-5
dc.identifier.urihttps://hdl.handle.net/11508/59898
dc.identifier.volume16
dc.identifier.wosWOS:001654735500001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNature Portfolio
dc.relation.ispartofScientific Reports
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260511
dc.subjectHepatitis C virus
dc.subjectBayesian regularization
dc.subjectRadial basis
dc.subjectOptimization
dc.subjectNumerical outputs
dc.titleDesigning a novel radial basis neural structure for solving the dynamical hepatitis C virus model
dc.typeArticle

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