The Ala-9Val polymorphism in the mitochondrial targeting sequence (MTS) of the manganese superoxide dismutase gene is not associated with juvenile-onset asthma

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dc.contributor.authorGurel, A
dc.contributor.authorTomac, N
dc.contributor.authorYilmaz, HR
dc.contributor.authorTekedereli, I
dc.contributor.authorAkyol, O
dc.contributor.authorArmutcu, F
dc.contributor.authorElyas, H
dc.date.accessioned2026-08-12T17:29:01Z
dc.date.issued2004
dc.departmentFırat Üniversitesi
dc.description.abstractBackground: We aimed to investigate the possible association between Mn-SOD polymorphism in the mitochondrial targeting sequence and asthma. Methods: Alanine or valine polymorphism in the signal peptide of Mn-SOD gene was evaluated using a primer pair to amplify a 107-bp fragment followed by digestion with NgoM IV Results: No significant difference in genotype frequencies was found between patients and controls. Conclusion: These results suggest no major modifying role for the Mn-SOD gene polymorphism in patients with asthma. (C) 2004 The Canadian Society of Clinical Chemists. All rights reserved.
dc.identifier.doi10.1016/j.clinbiochem.2004.08.002
dc.identifier.endpage1120
dc.identifier.issn0009-9120
dc.identifier.issn1873-2933
dc.identifier.issue12
dc.identifier.pmid15589819
dc.identifier.scopus2-s2.0-20844446132
dc.identifier.scopusqualityQ2
dc.identifier.startpage1117
dc.identifier.urihttps://doi.org/10.1016/j.clinbiochem.2004.08.002
dc.identifier.urihttps://hdl.handle.net/11508/55538
dc.identifier.volume37
dc.identifier.wosWOS:000225903000011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofClinical Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260511
dc.subjectAsthma
dc.subjectoxidative stress
dc.subjectmanganese superoxide dismutase
dc.subjectpolymorphism
dc.titleThe Ala-9Val polymorphism in the mitochondrial targeting sequence (MTS) of the manganese superoxide dismutase gene is not associated with juvenile-onset asthma
dc.typeArticle

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