A new method based on deep learning and image processing for detection of strabismus with the Hirschberg test

Abstract

Strabismus is a condition in which one or both eyes do not work in parallel or in harmony. People with strabismus have one eye looking straight ahead while the other eye looks inwards, outwards, upwards or downwards. This condition can affect both eyes. Strabismus is a common eye condition that affects about 4 % of the world's population. Tests such as Hirschberg, Cover and Krimsky are used to detect strabismus. In the Hirschberg test, a light source is held at a distance of 50 cm so that it falls on the centre of each eye. The horizontal and vertical distance between the centre of gravity of the light reflected from the cornea and the centre of the pupil indicates the degree of strabismus. In this study, deep learning and image processing algorithms are used to detect the eye, corneal reflection, iris and pupil on a patient's facial image. Based on the Hirschberg test, the horizontal and vertical shifts for both eyes were measured to determine the patient's degree of strabismus. In this way, the Hirschberg test used in strabismus screening was performed automatically by software. The correct detection of the pupil and the light reflected from the cornea by the algorithm means that the eye has been measured correctly. The software was tested on the facial images of 88 strabismic patients of different sexes and ages. 91 % of the 88 patients, or 80 patients, had their left eye measured correctly. 90 % of the 88 patients, or 79 patients, had their right eye measured correctly. The results for each eye obtained from the correct measurements were found to have an error of maximum +/- 2 degrees. This error is due to the fact that a real eye is in three-dimensional space, while the digital eye image is in two-dimensional space, and was only observed in the test results of some patients. This algorithm can be tested on patients of all ages and is not affected by morphological differences in the patients' faces. Successful results have been observed experimentally that this newly proposed method can be used in strabismus screening.