Synthesis of Heterocyclic-Substituted Novel Hydroxysteroids with Regioselective and Stereoselective Reactions
| dc.contributor.author | Kolo, Abubakar Mohammed | |
| dc.contributor.author | Ipek, Emine | |
| dc.contributor.author | Capan, Irfan | |
| dc.contributor.author | Servi, Suleyman | |
| dc.date.accessioned | 2026-08-12T17:33:30Z | |
| dc.date.issued | 2018 | |
| dc.department | Fırat Üniversitesi | |
| dc.description.abstract | Polyhydroxy steroids bearing the 3,5,6-trihydroxy pattern were synthesized from different heterocyclic-substituted unsaturated steroid by an easy and simple method with high yields. The endocyclic double bond of thiophene-substituted and quinoline-substituted steroids were converted to the trans-diaxial diol by the regioselective and stereoselective reactions with m-chloroperoxybenzoic acid in the basic medium. | |
| dc.description.sponsorship | Firat University Research Project Coordination Unit [FF.14.03, FF.15.08] | |
| dc.description.sponsorship | We are indebted to the Firat University Research Project Coordination Unit (project numbers FF.14.03 and FF.15.08) for financial support of this work. | |
| dc.identifier.doi | 10.1002/jhet.3070 | |
| dc.identifier.endpage | 497 | |
| dc.identifier.issn | 0022-152X | |
| dc.identifier.issn | 1943-5193 | |
| dc.identifier.issue | 2 | |
| dc.identifier.orcid | 0000-0002-9555-1555 | |
| dc.identifier.scopus | 2-s2.0-85039978689 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 492 | |
| dc.identifier.uri | https://doi.org/10.1002/jhet.3070 | |
| dc.identifier.uri | https://hdl.handle.net/11508/57043 | |
| dc.identifier.volume | 55 | |
| dc.identifier.wos | WOS:000424271200014 | |
| dc.identifier.wosquality | Q2 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | Wiley | |
| dc.relation.ispartof | Journal of Heterocyclic Chemistry | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.snmz | KA_WoS_20260511 | |
| dc.subject | Prostate-Cancer | |
| dc.subject | Biological Evaluation | |
| dc.subject | Transition-State | |
| dc.subject | Chiral Ketones | |
| dc.subject | Epoxidation | |
| dc.subject | Steroids | |
| dc.subject | Agents | |
| dc.subject | Galeterone | |
| dc.subject | Design | |
| dc.title | Synthesis of Heterocyclic-Substituted Novel Hydroxysteroids with Regioselective and Stereoselective Reactions | |
| dc.type | Article |
