Extended-release trazodone in the treatment of major depressive disorder

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dc.contributor.authorKaramustafalioglu, Oguz
dc.contributor.authorDilbaz, Nesrin
dc.contributor.authorCaykoylu, Ali
dc.contributor.authorAlkin, Tunc
dc.contributor.authorGonul, Ali Saffet
dc.contributor.authorAtmaca, Murad
dc.date.accessioned2026-08-12T16:42:01Z
dc.date.issued2019
dc.departmentFırat Üniversitesi
dc.description.abstractMajor depressive disorder is a common psychiatric disorder. The aim of the treatment is to improve daily functions with remissions in symptoms, and antidepressants are the first-line treatments for a major depressive episode (moderate-severe depressive episode). In this paper, the pharmacological properties, clinical efficacy and safety of extended-release trazodone (TzCOAD) are studied. Expert opinion: A single daily dose of TzCOAD may provide similar efficacy and increased tolerability to immediate-release trazodone (TzIR) and other antidepressants.
dc.identifier.doi10.5455/apd.302644467
dc.identifier.endpage459
dc.identifier.issn1302-6631
dc.identifier.issue5
dc.identifier.orcid0000-0001-6151-7060
dc.identifier.scopus2-s2.0-85073419592
dc.identifier.scopusqualityN/A
dc.identifier.startpage453
dc.identifier.trdizinid313372
dc.identifier.urihttps://doi.org/10.5455/apd.302644467
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/313372
dc.identifier.urihttps://hdl.handle.net/11508/46072
dc.identifier.volume20
dc.identifier.wosWOS:000486651400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isotr
dc.publisherCumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali
dc.relation.ispartofAnadolu Psikiyatri Dergisi-Anatolian Journal of Psychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260511
dc.subjectmajor depressive disorder
dc.subjectextended-release trazodone (single dose of TzCOAD per day)
dc.subjectimmediate-release trazodone (three doses of TzIR per day)
dc.titleExtended-release trazodone in the treatment of major depressive disorder
dc.title.alternativeMajor depresif bozukluk tedavisinde uzatılmış salımlı trazodon
dc.typeReview Article

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