A novel and efficient synthesis of 3-aryl and 3-heteroaryl substituted-1H-indazoles and their Mannich derivatives

dc.contributor.authorServi, S
dc.contributor.authorAkgün, ZR
dc.date.accessioned2026-08-12T17:10:32Z
dc.date.issued2002
dc.departmentFırat Üniversitesi
dc.description.abstractA general and highly convenient procedure for the synthesis of 3-heteroaryl and 3-aryl substituted-1H-indazoles has been developed. These compounds (3a-f) were synthesized in good yield by refluxing the NaHSO3 adduct of heteroaromatic and aromatic aldehyde and phenyl hydrazine in DMF. This procedure is more general and shorter than earlier methods. Five new 3-hetero-aryl substituted-1H-indazoles were synthesized and characterized. New Mannich derivatives of 3-(1H-pyrrol-2-yl)-1H-indazole (3a) and 3-(1H-indol-3-yl)1H-indazole (3b) were prepared from morpholine and formaldehyde.
dc.identifier.doi10.1081/SCC-120014767
dc.identifier.endpage3405
dc.identifier.issn0039-7911
dc.identifier.issue22
dc.identifier.scopus2-s2.0-0036035290
dc.identifier.scopusqualityQ3
dc.identifier.startpage3399
dc.identifier.urihttps://doi.org/10.1081/SCC-120014767
dc.identifier.urihttps://hdl.handle.net/11508/50777
dc.identifier.volume32
dc.identifier.wosWOS:000178981000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMarcel Dekker Inc
dc.relation.ispartofSynthetic Communications
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260511
dc.titleA novel and efficient synthesis of 3-aryl and 3-heteroaryl substituted-1H-indazoles and their Mannich derivatives
dc.typeArticle

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